Embark on our only Central American expedition that travels solely through Panama, connecting you more deeply with the region’s wildlife, culture and famed modern engineering marvel. Aboard the National Geographic Quest, transit the historic Panama Canal by day and by night. Learn about the country’s indigenous and colonial history while visiting local communities and two UNESCO World Heritage sites. Encounter monkeys, iguanas, tropical birds and more as you venture into lush rainforests, a wildlife refuge and an important national park. In the surrounding turquoise waters, snorkel pristine coral reefs which shelter an array of colorful marine life.
Highlights
• Transit the legendary Panama Canal—plus enjoy an exclusive stop at the Smithsonian Tropical Research Institute’s Barro Colorado Island
• Discover the storied Spanish architecture and fascinating pirate history of Portobelo, a UNESCO World Heritage site
• Meet the indigenous Emberá people of Darién in Playa Muerto Village and learn about their customs, traditions and deep reverence for their natural surroundings
• Sea kayak, hike, Zodiac cruise and snorkel in the tranquil Pearl Islands, a network of 200 islands known for turquoise waters, white-sand beaches and an enduring connection to the pearl trade
Arrive in Panama City, the capital of Panama this afternoon and transfer to Port Balboa to embark the National Geographic Quest this evening. You may opt for a culturally-immersive pre-voyage extension in Panama City and San Lorenzo, a UNESCO-designated World Heritage Site. Later on, you'll enter the Panama Canal at the Gatun Locks.
Arrival Time: Arrive by 12:00 p.m.
Arrival City: Panama City, Panama
This morning, arrive along the coast of the Darién Province. Punta Patiño Nature Reserve is Panama’s largest private nature reserve and boasts a rich tapestry of habitats that foster biodiversity. Today you will reach the local beaches by Zodiac. Overhead, search for a variety of birds including mangrove hawks, laughing falcons and roseate spoonbills, or, by land, look for crab-eating raccoons and crocodiles. Additional opportunities may be available to walk the beach, kayak in the shallow bay or continue to explore by Zodiac.
Today, choose hikes and Zodiac cruises at the Smithsonian Tropical Research Institute facility on Barro Colorado Island, or take a boat ride to Gamboa, where the Chagres River meets the Panama Canal, and hike on the Panama Rainforest Discovery Center trails. This evening, continue through the complex lock system of the Canal and venture into the Gulf of Panama.
Approximately 200 islands make up the idyllic Pearl Islands. Explore several of the islands in the archipelago, including Isla del Rey and Isla Pacheca, as you learn about the history of the native populations and eventually the Spaniards and African slaves who arrived for the pearl trade. Deep rainforests, lush rivers, white sandy beaches and shallow reefs provide great opportunities for hiking, sea kayaking, stand-up paddleboarding, Zodiac river cruises, beach activities and snorkeling.
Playa Muerto village is located in Darién National Park, the largest protected area in Central America and a UNESCO World Heritage site. The park contains an exceptional array of habitats, from sandy beaches and mangroves to dense tropical forests teeming with wildlife. It is also home to the indigenous Emberá and Wounaan tribes. You’ll be greeted by village leaders from the Emberá who will share their customs, traditions and stories about their deep respect for their natural surroundings. Later on, enjoy short nature walks, go birding or choose to join a longer hike into the rainforest in search of the elusive harpy eagle, one of the world’s most powerful eagles.
This morning, explore the historically important town of Portobelo, located on the northern coast of the isthmus of Panama. Portobelo is known for its Spanish colonial military architecture, which is designated collectively as a UNESCO World Heritage site. Visit several of the fortifications as well as the old Customs House and hear the tales of Portobelo’s rich pirate history. During your visit, enjoy a Congo dance presentation, deeply rooted in the traditions of the Afro-Panamanian community, holding great historical significance.
Later on, set sail for the Panama Canal. As cargo ships tend to pass through the canal during the day, you'll most likely begin your crossing at night, when the canal is dramatically lit. By special arrangement, National Geographic Quest will anchor in Gatún Lake near the Barro Colorado Nature Monument overnight.
After breakfast, disembark in Colón and transfer to the airport in Panama City for your flight home. Ask your expedition specialist about enjoying a culturally-immersive post-voyage extension in Panama City and San Lorenzo, a UNESCO-designated World Heritage Site.
Departure Time: Depart anytime after 2:30 p.m.
Departure City: Panama City, Panama
Itineraries are subject to change.
06 December, 2026 to 13 December, 2026
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
13 December, 2026 to 20 December, 2026(reverse)
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
29 January, 2027 to 05 February, 2027(reverse)
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
05 November, 2027 to 12 November, 2027(reverse)
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
29 January, 2028 to 05 February, 2028(reverse)
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
09 March, 2028 to 16 March, 2028
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
16 March, 2028 to 23 March, 2028(reverse)
National Geographic Quest
|
|
|
Book now
|
#301-306 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#307-315 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, two portholes, full length mirror, and reading lights.
#201-206 — Cabins feature two single beds that can convert to a Queen, a writing desk, two nightstands, a large view window, full-length mirror, and reading lights.
#207-229 — Cabins feature two single beds that can convert to a Queen, a writing desk, closet, two nightstands, full-length mirror, reading lights, sliding glass door, and a small, private balcony.
#101-108 — These suites feature two single beds that can convert to a Queen, a convertible sofa bed that can accommodate a third person, large view windows, closet, two nightstands, full-length mirror, reading lights, writing desk, ample storage space, espresso maker and an oversized bathroom. Guests receive complimentary laundry and priority access to one spa appointment per departure.
Inclusions
• All accommodations, meals, and non-alcoholic beverages aboard ships
• Use of snorkeling equipment, wet suits, and kayaks (where available)
• Services of our expert expedition team and guest speakers
• Services of a ship physician on most voyages
• Certain hotels and meals ashore as indicated in the itinerary
• Round-trip transfers based on group flights
• Shore excursions, sightseeing, entrance fees, and special access permits
• Taxes, service charges, and tips (except for ship’s crew, at our guests’ discretion)
_____________
Exclusions
• Air transportation (except when we indicated in the itinerary, as included) Extensions
• Passport, visa, and immigration fees
• Travel Protection Plan
• Special and unique excursions such as scuba diving, flightseeing, etc. (where offered)
• Alcoholic beverages (alcohol is included on select ships)
• Items of personal nature
• Phone and Internet Service
• Laundry
• Gratuity for ship’s crew, at our guests’ discretion (crew tips are included on select ships)